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Opioid Crisis
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Opioids are useful in controlling pain,
but carry significant risks:
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- Fatal respiratory and cardiovascular reactions
- Weaponization and use by terrorists
- Tolerance in treatment of chronic pain / end-of-life pain control
- Gastrointestinal and dermal disruption
- Dependence / addiction
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Opioid-induced side effects have created unmet medical needs of crisis proportions, affecting millions of people annually.
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The Problem: Overdose Deaths
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Overdose deaths caused by synthetic opioids (primarily fentanyl) have become a massive crisis, approaching 40,000 in 2019
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space][vc_single_image image=”84″ img_size=”full” qode_css_animation=””][vc_column_text]Number Among All Ages, 1999-2019: Includes deaths with underlying causes of unintentional drug poisoning (X40–X44), suicide drug poisoning (X60–X64), homicide drug poisoning (X85), or drug poisoning of undetermined intent (Y10–Y14), as coded in the International Classification of Diseases, 10th Revision. Source: Centers for Disease Control and Prevention, National Center for Health Statistics. Multiple Cause of Death 1999-2019 on CDC WONDER Online Database, released 12/2020.[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_separator type=”normal”][vc_empty_space][vc_column_text]
The Problem: OIRD
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46% of patients receiving opioids on the hospital general care floor experience opioid-induced respiratory depression (OIRD)*:
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- OIRD is a life-threatening side effect of opioids
- It affects millions of hospitalized patients every year
- OIRD extends hospital stays by 3 days on average
- Longer hospitalization increases mean cost by over $6,000
[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_single_image image=”86″ img_size=”full” qode_css_animation=””][vc_column_text]*Source: Medtronic Prodigy Study, 2020[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_separator type=”normal”][vc_empty_space][vc_column_text]
The Problem: Weaponization
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The opioid crisis has a new and even uglier dimension – weaponization – and the focused interest of the United States military.
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column width=”2/3″][vc_single_image image=”87″ img_size=”full” qode_css_animation=””][vc_column_text]Russian special forces soldiers carrying out hostages killed by a highly potent weaponized opioid in a Moscow theatre after a three-day stand off with Chechen terrorists. (Credit: Anton Denisov/AFP/Getty Images)[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_column_text]
NIH: “These public health threat agents are highly toxic chemicals that could cause mass casualties after either deliberate terrorism-related release or inadvertently.”
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